Assay Detail
Functional
CHEMBL683872
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The compound was tested in vitro for growth inhibition against HL-60(human promyelocytic leukemia) cell line in the presence of UVA(ultra violet A irradiated)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
New tetracyclic analogues of photochemotherapeutic drugs 5-MOP and 8-MOP: synthesis, DNA interaction, and antiproliferative activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.65 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL136584 | — | — | 1 | 6.22 |
| CHEMBL24171 | BERGAPTEN | 3.0 | 1 | 5.47 |
| CHEMBL416 | METHOXSALEN | 4.0 | 1 | 5.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL136584 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL24171 | BERGAPTEN | IC50 | = | 3350.0 | nM | 5.47 |
| CHEMBL416 | METHOXSALEN | IC50 | = | 5400.0 | nM | 5.27 |