Assay Detail
Binding
CHEMBL684233
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Binding activity against Glucose transporter in human erythrocyte membrane using [125I]7-IHPP-Fsk as the radioligand.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Solute carrier family 2, facilitated glucose transporter member 1 (CHEMBL2535) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
(Aminoalkyl)carbamates of forskolin: intermediates for the synthesis of functionalized derivatives of forskolin with different specificities for adenylyl cyclase and the glucose transporter.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 5.87 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL107985 | — | — | 1 | 6.52 |
| CHEMBL110686 | — | — | 1 | 6.30 |
| CHEMBL107566 | — | — | 1 | 5.89 |
| CHEMBL111514 | — | — | 1 | 4.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL107985 | — | Kd | = | 300.0 | nM | 6.52 |
| CHEMBL110686 | — | Kd | = | 500.0 | nM | 6.30 |
| CHEMBL107566 | — | Kd | = | 1300.0 | nM | 5.89 |
| CHEMBL111514 | — | Kd | = | 17000.0 | nM | 4.77 |