Assay Detail
Binding
CHEMBL684234
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Inhibition of [125I]7-IHPP-Fsk binding to glucose transporter of human erythrocyte membrane
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Solute carrier family 2, facilitated glucose transporter member 1 (CHEMBL2535) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
(Aminoalkyl)carbamates of forskolin: intermediates for the synthesis of functionalized derivatives of forskolin with different specificities for adenylyl cyclase and the glucose transporter.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 13 | 5.94 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL111738 | — | — | 1 | 7.00 |
| CHEMBL327672 | — | — | 1 | 6.62 |
| CHEMBL324659 | — | — | 1 | 6.40 |
| CHEMBL111425 | — | — | 1 | 6.10 |
| CHEMBL327142 | — | — | 1 | 5.96 |
| CHEMBL326463 | — | — | 1 | 5.55 |
| CHEMBL52606 | COLFORSIN | 2.0 | 1 | 5.30 |
| CHEMBL91909 | — | — | 1 | 4.55 |
| CHEMBL326703 | — | — | 1 | - |
| CHEMBL328561 | — | — | 1 | - |
| CHEMBL92719 | — | — | 1 | - |
| CHEMBL324463 | — | — | 1 | - |
| CHEMBL322952 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL111738 | — | Kd | = | 100.0 | nM | 7.00 |
| CHEMBL327672 | — | Kd | = | 240.0 | nM | 6.62 |
| CHEMBL324659 | — | Kd | = | 400.0 | nM | 6.40 |
| CHEMBL111425 | — | Kd | = | 800.0 | nM | 6.10 |
| CHEMBL327142 | — | Kd | = | 1100.0 | nM | 5.96 |
| CHEMBL326463 | — | Kd | = | 2800.0 | nM | 5.55 |
| CHEMBL52606 | COLFORSIN | Kd | = | 5000.0 | nM | 5.30 |
| CHEMBL91909 | — | Kd | = | 28000.0 | nM | 4.55 |
| CHEMBL326703 | — | Kd | > | 100000.0 | nM | - |
| CHEMBL328561 | — | Kd | > | 100000.0 | nM | - |
| CHEMBL92719 | — | Kd | > | 100000.0 | nM | - |
| CHEMBL324463 | — | Kd | > | 100000.0 | nM | - |
| CHEMBL322952 | — | Kd | > | 100000.0 | nM | - |