Assay Detail
Binding
CHEMBL685519
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Dissociation constant for binding to SH2 domain of Growth factor receptor bound protein 2, Grb2
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
Growth factor receptor-bound protein 2 (CHEMBL3663) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Acquisition of high-affinity, SH2-targeted ligands via a spatially focused library.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 4.95 | 4.95 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL12253 | — | — | 1 | 4.95 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL12253 | — | Kd | = | 11300.0 | nM | 4.95 |