Assay Detail
Binding
CHEMBL686006
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Inhibitory activity was measured on recombinant human Glutathione S-transferase P
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Isozyme-specific glutathione-S-transferase inhibitors: design and synthesis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 5.75 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL442360 | — | — | 1 | 6.92 |
| CHEMBL58951 | — | — | 1 | 6.38 |
| CHEMBL58507 | — | — | 1 | 6.07 |
| CHEMBL58135 | — | — | 1 | 5.00 |
| CHEMBL301229 | — | — | 1 | 4.40 |
| CHEMBL60581 | — | — | 1 | - |
| CHEMBL58451 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL442360 | — | Ki | = | 120.0 | nM | 6.92 |
| CHEMBL58951 | — | Ki | = | 420.0 | nM | 6.38 |
| CHEMBL58507 | — | Ki | = | 850.0 | nM | 6.07 |
| CHEMBL58135 | — | Ki | = | 10000.0 | nM | 5.00 |
| CHEMBL301229 | — | Ki | = | 40000.0 | nM | 4.40 |
| CHEMBL60581 | — | Ki | = | 550000.0 | nM | - |
| CHEMBL58451 | — | Ki | = | 710000.0 | nM | - |