Assay Detail
Functional
CHEMBL686360
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Functional biological activity for mu opioid receptor was determined in vitro, on guinea pig ileum (GPI).
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Helix-inducing alpha-aminoisobutyric acid in opioid mimetic deltorphin C analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.37 | 8.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL420606 | — | — | 1 | 8.35 |
| CHEMBL317956 | DELTORPHIN C | — | 1 | 6.38 |
| CHEMBL315603 | — | — | 1 | - |
| CHEMBL441889 | — | — | 1 | - |
| CHEMBL315225 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL420606 | — | IC50 | = | 4.5 | nM | 8.35 |
| CHEMBL317956 | DELTORPHIN C | IC50 | = | 420.0 | nM | 6.38 |
| CHEMBL315603 | — | IC50 | > | 10.0 | nM | - |
| CHEMBL441889 | — | IC50 | > | 10.0 | nM | - |
| CHEMBL315225 | — | IC50 | > | 10.0 | nM | - |