Assay Detail
Binding
CHEMBL686443
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In vitro Growth factor receptor bound protein 2-binding affinity in ELISA method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Growth factor receptor-bound protein 2 (CHEMBL3663) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Macrocyclization in the design of non-phosphorus-containing Grb2 SH2 domain-binding ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.01 | 8.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL70024 | — | — | 1 | 8.37 |
| CHEMBL55627 | — | — | 1 | 8.00 |
| CHEMBL303150 | — | — | 1 | 7.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL70024 | — | IC50 | = | 4.3 | nM | 8.37 |
| CHEMBL55627 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL303150 | — | IC50 | = | 22.1 | nM | 7.66 |