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Assay Detail

CHEMBL686848

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In vitro inhibitory concentration against proliferation of HL60R cells along with 5 (uM) verapamil
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HL-60
Confidence 1 — Organism
Curated By Intermediate

Target

HL-60 (CHEMBL383)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agents.
Roberti M, Pizzirani D, Simoni D, Rondanin R, Baruchello R, Bonora C, Buscemi F, Grimaudo S, Tolomeo M.
J Med Chem (2003) 46 : 3546 -3554
PubMed 12877593 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.70 7.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL116888 1 7.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL116888 IC50 = 20.0 nM 7.70