Assay Detail

CHEMBL687247

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Functional

Tested in vitro for cytostatic activity against 60-cell line

ChEMBL ↗

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Target

HL-60 (CHEMBL383) ↗

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Primary target HL-60

CHEMBL383

Anchored from Assay target.

Protein identity HL-60

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	HL-60
Confidence	1 — Organism
Curated By	Intermediate

Target

HL-60 (CHEMBL383) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Cholestane glycosides with potent cytostatic activities on various tumor cells from Ornithogalum saundersiae bulbs

Mimaki Y, Kuroda M, Kameyama A, Sashida Y, Hirano T, Oka K, Maekawa R, Wada T, Sugita K, Beutler JA
Bioorg Med Chem Lett (1997) 7 : 633 -636
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	9.11	9.11

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL2368220	—	—	1	9.11

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL2368220	—	IC50	=	0.78	nM	9.11