Assay Detail
Binding
CHEMBL687337
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro antihistamine activity, by activation of guinea pig cerebral cortex adenylate cyclase by histamine mediated by both H1 and H2 receptors
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Cerebral cortex |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and biological properties of thiophene ring analogues of mianserin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.72 | 6.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL544428 | MIANSERIN HYDROCHLORIDE | -1.0 | 1 | 6.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL544428 | MIANSERIN HYDROCHLORIDE | IC50 | = | 190.0 | nM | 6.72 |