Assay Detail

CHEMBL687536

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Binding

Inhibition of human recombinant 92 kDa gelatinase MMP-9 at 100 uM

ChEMBL ↗

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Target

Matrix metalloproteinase-9 (CHEMBL321) ↗

Open DB target context

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Primary target Matrix metalloproteinase-9

CHEMBL321

Anchored from Assay target.

Protein identity Matrix metalloproteinase-9

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	9 — Direct single protein target
Curated By	Expert

Target

Matrix metalloproteinase-9 (CHEMBL321) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Inhibition of metalloproteinase by futoenone derivatives

Yeh L, Chen J, Baculi F, Gingrich DE, Shen T
Bioorg Med Chem Lett (1995) 5 : 1637 -1642
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	9.70	9.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL19611	ILOMASTAT	2.0	1	9.70

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL19611	ILOMASTAT	IC50	=	0.2	nM	9.70