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Assay Detail

CHEMBL688060

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory concentration against growth of cultured HL-60 cells at 144 hrs.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HL-60
Confidence 1 — Organism
Curated By Intermediate

Target

HL-60 (CHEMBL383)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthetic polyamine analogues as antineoplastics.
Bergeron RJ, Neims AH, McManis JS, Hawthorne TR, Vinson JR, Bortell R, Ingeno MJ.
J Med Chem (1988) 31 : 1183 -1190
PubMed 3373487 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.52 6.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL18794 BIS(ETHYL)SPERMINE 1 6.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL18794 BIS(ETHYL)SPERMINE IC50 = 300.0 nM 6.52