Assay Detail
Functional
CHEMBL688553
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of EGF-dependent proliferation of human and guinea pig keratinocytes; range 7-15 uM
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
New dermatological agents for the treatment of psoriasis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.16 | 5.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL77030 | TYRPHOSTIN 47 | — | 1 | 5.16 |
| CHEMBL56543 | — | — | 1 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL77030 | TYRPHOSTIN 47 | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL56543 | — | IC50 | = | 7000.0 | nM | 5.16 |