Assay Detail
Functional
CHEMBL689648
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of [3H]arachidonic acid production by stimulated HL60 cells.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Design and synthesis of a novel and potent series of inhibitors of cytosolic phospholipase A(2) based on a 1,3-disubstituted propan-2-one skeleton.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.54 | 4.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL281211 | ARACHIDONYL TRIFLUOROMETHYLKETONE | — | 1 | 4.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL281211 | ARACHIDONYL TRIFLUOROMETHYLKETONE | IC50 | = | 29000.0 | nM | 4.54 |