Assay Detail
Functional
CHEMBL689901
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The compound was tested for its inhibitory activity against HL-60 human leukemia cell line
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis of the novel analogues of dysidiolide and their structure-activity relationship.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.34 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL86406 | — | — | 1 | 6.00 |
| CHEMBL1765353 | DYSIDIOLIDE | — | 1 | 5.15 |
| CHEMBL356927 | — | — | 1 | 4.88 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL86406 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL1765353 | DYSIDIOLIDE | IC50 | = | 7100.0 | nM | 5.15 |
| CHEMBL356927 | — | IC50 | = | 13100.0 | nM | 4.88 |