Assay Detail
Functional
CHEMBL690904
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration against HSV-1 TK (WT) catalyzed [3H]-GCV phosphorylation
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human alphaherpesvirus 1 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Acyclic nucleoside analogues as novel inhibitors of human mitochondrial thymidine kinase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.75 | 5.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL52609 | DOXRIBTIMINE | 2.0 | 1 | 5.75 |
| CHEMBL68908 | DEOXYGUANOSINE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL52609 | DOXRIBTIMINE | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL68908 | DEOXYGUANOSINE | IC50 | = | 364000.0 | nM | - |