Assay Detail
Functional
CHEMBL691357
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Inhibitory activity against HCMV DNA synthesis in virus infected cells
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEL |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Haloanilino derivatives of pyrimidines, purines, and purine nucleoside analogs: synthesis and activity against human cytomegalovirus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.74 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL51501 | — | — | 1 | 5.30 |
| CHEMBL53912 | — | — | 1 | 5.04 |
| CHEMBL51613 | — | — | 1 | 4.92 |
| CHEMBL298714 | — | — | 1 | 4.60 |
| CHEMBL54127 | — | — | 1 | 4.60 |
| CHEMBL301283 | — | — | 1 | 4.55 |
| CHEMBL53307 | — | — | 1 | 4.48 |
| CHEMBL52034 | — | — | 1 | 4.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL51501 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL53912 | — | IC50 | = | 9100.0 | nM | 5.04 |
| CHEMBL51613 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL298714 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL54127 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL301283 | — | IC50 | = | 28000.0 | nM | 4.55 |
| CHEMBL53307 | — | IC50 | = | 33000.0 | nM | 4.48 |
| CHEMBL52034 | — | IC50 | = | 40000.0 | nM | 4.40 |