HEL · CELL-LINE · Homo sapiens
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Confirm a stable target identifier before relying on this context across project surfaces.
HEL
Review this target as HEL.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats HEL as ChEMBL target CHEMBL613888. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | HEL |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as HEL.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL31634 | 9.0 | IC50 | 1.0 | Clinical |
| CHEMBL325041 | 8.79 | IC50 | 1.611 | Clinical |
| CHEMBL888 | 8.75 | IC50 | 1.791 | Approved |
| CHEMBL3142406 | 8.7 | EC50 | 2.0 | Preclinical |
| CHEMBL31634 | 8.52 | EC50 | 3.0 | Clinical |
| CHEMBL94657 | 8.38 | IC50 | 4.136 | Clinical |
| CHEMBL1094408 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL65 | 8.2 | IC50 | 6.311 | Preclinical |
| CHEMBL1972860 | 8.15 | IC50 | 7.077 | Clinical |
| CHEMBL144817 | 8.1 | EC50 | 8.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 791 | 735 | 5.6 |
| organism-based format | 32 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 167 | 6 | 4.4 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 12 | 2 | 5.7 |