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Assay Detail

CHEMBL691374

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anti HIV activity against cloned FTC/3TC-resistant mutant M184V HIV-1
3
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human immunodeficiency virus 1
Confidence 1 — Organism
Curated By Intermediate

Target

Human immunodeficiency virus 1 (CHEMBL378)
Type ORGANISM
Organism Human immunodeficiency virus 1

Publication

Synthesis and antiviral activity of oxaselenolane nucleosides.
Chu CK, Ma L, Olgen S, Pierra C, Du J, Gumina G, Gullen E, Cheng YC, Schinazi RF.
J Med Chem (2000) 43 : 3906 -3912
PubMed 11052795 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 3 4.30 4.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL433859 3 4.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL433859 EC50 = 50000.0 nM 4.30
CHEMBL433859 EC50 = 108000.0 nM -
CHEMBL433859 EC50 > 50000.0 nM -