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Assay Detail

CHEMBL691390

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory concentration against HIV-1 Bal/Mono
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human immunodeficiency virus 1
Confidence 1 — Organism
Curated By Intermediate

Target

Human immunodeficiency virus 1 (CHEMBL378)
Type ORGANISM
Organism Human immunodeficiency virus 1

Publication

Synthesis and antiviral activity of 4-benzyl pyridinone derivatives as potent and selective non-nucleoside human immunodeficiency virus type 1 reverse transcriptase inhibitors.
Dollé V, Nguyen CH, Legraverend M, Aubertin AM, Kirn A, Andreola ML, Ventura M, Tarrago-Litvak L, Bisagni E.
J Med Chem (2000) 43 : 3949 -3962
PubMed 11052800 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.89 6.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL57733 1 6.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL57733 IC50 = 130.0 nM 6.89