Assay Detail
Functional
CHEMBL691808
Review assay metadata, readout intent, target linkage, and publication context from the same page.
HCMV plaque assay was performed using HFF cells and effect was calculated as a percentage of reduction in number of plaques
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HFF |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Deoxy sugar analogues of triciribine: correlation of antiviral and antiproliferative activity with intracellular phosphorylation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.85 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL462018 | TRICIRIBINE PHOSPHATE | 2.0 | 1 | 6.10 |
| CHEMBL331237 | TRICIRIBINE | — | 1 | 5.60 |
| CHEMBL314567 | — | — | 1 | - |
| CHEMBL2367598 | — | — | 1 | - |
| CHEMBL2112098 | — | — | 1 | - |
| CHEMBL1790617 | — | — | 1 | - |
| CHEMBL315509 | — | — | 1 | - |
| CHEMBL609194 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL462018 | TRICIRIBINE PHOSPHATE | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL331237 | TRICIRIBINE | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL314567 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2367598 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2112098 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL1790617 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL315509 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL609194 | — | IC50 | > | 100000.0 | nM | - |