Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL692127

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity to human epidermoid carcinoma cells (HEP-2)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HEp-2
Confidence 1 — Organism
Curated By Intermediate

Target

HEp-2 (CHEMBL614735)
Type CELL-LINE
Organism Homo sapiens

Publication

Phosphonate analogs of carbocyclic nucleotides.
Elliott RD, Rener GA, Riordan JM, Secrist JA, Bennett LL, Parker WB, Montgomery JA.
J Med Chem (1994) 37 : 739 -744
PubMed 8145223 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.82 5.62

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL350934 1 5.62
CHEMBL277264 1 4.02

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL350934 IC50 = 2400.0 nM 5.62
CHEMBL277264 IC50 = 95000.0 nM 4.02