Assay Detail
Functional
CHEMBL692466
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration to inhibit replication of viral strain HIV-2 ROD in acutely infected C8166T cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 2 |
| Cell Type | C8166T |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Target
Human immunodeficiency virus 2 (CHEMBL380) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 2 |
Publication
2',6'-Dimethylphenoxyacetyl: a new achiral high affinity P(3)-P(2) ligand for peptidomimetic-based HIV protease inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.06 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL267571 | — | — | 1 | 8.52 |
| CHEMBL13134 | PALINAVIR | 2.0 | 1 | 7.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL267571 | — | EC50 | = | 3.0 | nM | 8.52 |
| CHEMBL13134 | PALINAVIR | EC50 | = | 25.0 | nM | 7.60 |