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Assay Detail

CHEMBL692468

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
The binding affinity is evaluated for viral strains HIV-2 ROD.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human immunodeficiency virus 2
Confidence 1 — Organism
Curated By Intermediate

Target

Human immunodeficiency virus 2 (CHEMBL380)
Type ORGANISM
Organism Human immunodeficiency virus 2

Publication

2',6'-Dimethylphenoxyacetyl: a new achiral high affinity P(3)-P(2) ligand for peptidomimetic-based HIV protease inhibitors.
Beaulieu PL, Anderson PC, Cameron DR, Croteau G, Gorys V, Grand-Maître C, Lamarre D, Liard F, Paris W, Plamondon L, Soucy F, Thibeault D, Wernic D, Yoakim C, Pav S, Tong L.
J Med Chem (2000) 43 : 1094 -1108
PubMed 10737742 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.89 9.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL13134 PALINAVIR 2.0 1 9.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL13134 PALINAVIR Ki = 0.13 nM 9.89