Assay Detail

CHEMBL692469

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Functional

Inhibitory concentration against HIV-2 protease in the absence of DMSO

ChEMBL ↗

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Target

Human immunodeficiency virus 2 (CHEMBL380) ↗

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Human immunodeficiency virus 2 (CHEMBL380) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Human immunodeficiency virus 2

CHEMBL380

Anchored from Assay target.

Protein identity Human immunodeficiency virus 2

Disease frame Disease evidence pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Human immunodeficiency virus 2
Confidence	1 — Organism
Curated By	Intermediate

Target

Human immunodeficiency virus 2 (CHEMBL380) ↗

Type	ORGANISM
Organism	Human immunodeficiency virus 2

Publication

Specific inhibition of HIV-1 protease by boronated porphyrins.

DeCamp DL, Babé LM, Salto R, Lucich JL, Koo MS, Kahl SB, Craik CS.
J Med Chem (1992) 35 : 3426 -3428
PubMed 1527792 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.64	6.64

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL326831	—	—	1	6.64

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL326831	—	IC50	=	230.0	nM	6.64