Assay Detail
Functional
CHEMBL692797
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Cytotoxicity against cell line HET-SR-2SC-LNM determined by MTT test
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cricetulus griseus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Effects of isoprenoid analogues of SDB-ethylenediamine on multidrug resistant tumor cells alone and in combination with chemotherapeutic drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.29 | 4.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL345994 | — | — | 1 | 4.46 |
| CHEMBL1280 | VERAPAMIL HYDROCHLORIDE | 4.0 | 1 | 4.32 |
| CHEMBL535167 | — | — | 1 | 4.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL345994 | — | IC50 | = | 35000.0 | nM | 4.46 |
| CHEMBL1280 | VERAPAMIL HYDROCHLORIDE | IC50 | = | 48000.0 | nM | 4.32 |
| CHEMBL535167 | — | IC50 | = | 80000.0 | nM | 4.10 |