Assay Detail

CHEMBL692903

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

In vitro inhibitory activity against proliferation of HIV viral cell

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

Human immunodeficiency virus (CHEMBL613758) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

Human immunodeficiency virus (CHEMBL613758) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Human immunodeficiency virus

CHEMBL613758

Anchored from Assay target.

Protein identity Human immunodeficiency virus

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Human immunodeficiency virus
Confidence	1 — Organism
Curated By	Intermediate

Target

Human immunodeficiency virus (CHEMBL613758) ↗

Type	ORGANISM
Organism	Human immunodeficiency virus

Publication

Synthesis and comparative evaluation of two antiviral agents: beta-L-Fd4C and beta-D-Fd4C.

Chen SH, Lin S, King I, Spinka T, Dutschman GE, Gullen EA, Cheng YC, Doyle TW.
Bioorg Med Chem Lett (1998) 8 : 3245 -3250
PubMed 9873711 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	2	6.70	6.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL38700	ELVUCITABINE	2.0	1	6.70
CHEMBL109831	DEXELVUCITABINE	2.0	1	6.70

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL38700	ELVUCITABINE	EC50	=	200.0	nM	6.70
CHEMBL109831	DEXELVUCITABINE	EC50	=	200.0	nM	6.70