Assay Detail
Functional
CHEMBL694652
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The binding affinity is evaluated for viral strains HIV-1 IIIB
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
2',6'-Dimethylphenoxyacetyl: a new achiral high affinity P(3)-P(2) ligand for peptidomimetic-based HIV protease inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 10.37 | 10.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL13134 | PALINAVIR | 2.0 | 1 | 10.51 |
| CHEMBL267571 | — | — | 1 | 10.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL13134 | PALINAVIR | Ki | = | 0.031 | nM | 10.51 |
| CHEMBL267571 | — | Ki | = | 0.06 | nM | 10.22 |