Assay Detail
Functional
CHEMBL694727
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Cytotoxicity against human foreskin fibroblasts (HFF) cells
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HFF |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Benzimidazole ribonucleosides: Observation of an unexpected nitration when performing non-aqueous diazotizations with t-butyl nitrite
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.28 | 4.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL375530 | DICHLORORIBOBENZIMIDAZOLE | — | 1 | 4.62 |
| CHEMBL603513 | — | — | 1 | 4.50 |
| CHEMBL608658 | — | — | 1 | 4.00 |
| CHEMBL608318 | — | — | 1 | 4.00 |
| CHEMBL605800 | — | — | 1 | - |
| CHEMBL182 | GANCICLOVIR | 4.0 | 1 | - |
| CHEMBL605799 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL375530 | DICHLORORIBOBENZIMIDAZOLE | IC50 | = | 24000.0 | nM | 4.62 |
| CHEMBL603513 | — | IC50 | = | 32000.0 | nM | 4.50 |
| CHEMBL608658 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL608318 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL605800 | — | IC50 | = | 127000.0 | nM | - |
| CHEMBL182 | GANCICLOVIR | IC50 | > | 100000.0 | nM | - |
| CHEMBL605799 | — | IC50 | > | 100000.0 | nM | - |