Assay Detail
Functional
CHEMBL694797
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of guinea pig Iks potassium channel expressed in Xenopus oocytes
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Cell Type | Oocyte |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Potassium voltage-gated channel subfamily KQT member 1 (CHEMBL5135) ↗| Type | SINGLE PROTEIN |
| Organism | Cavia porcellus |
Publication
Selective optimization of side activities: another way for drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.07 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL298475 | — | — | 1 | 6.92 |
| CHEMBL44297 | — | — | 1 | 5.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL298475 | — | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL44297 | — | IC50 | = | 6200.0 | nM | 5.21 |