Assay Detail
Functional
CHEMBL694823
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Compound was evaluated for inhibition of LTB4 induced chemotaxis of human neutrophils
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and pharmacologic activity of hydroxyacetophenone-substituted benzophenone/xanthone leukotriene B4 receptor antagonists
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.54 | 6.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL292768 | — | — | 1 | 6.50 |
| CHEMBL49210 | — | — | 1 | 6.05 |
| CHEMBL49302 | — | — | 1 | 5.22 |
| CHEMBL15766 | LY-255283 | — | 1 | 5.13 |
| CHEMBL60881 | — | — | 1 | 4.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL292768 | — | IC50 | = | 320.0 | nM | 6.50 |
| CHEMBL49210 | — | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL49302 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL15766 | LY-255283 | IC50 | = | 7400.0 | nM | 5.13 |
| CHEMBL60881 | — | IC50 | = | 16000.0 | nM | 4.80 |