Assay Detail
Functional
CHEMBL695386
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for inhibition against HIV-III B from C8 166 cell lines
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | human immunodeficiency virus type 3b |
| Cell Type | C8116 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Target
Human immunodeficiency virus 3 (CHEMBL612359) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 3 |
Publication
Pyrrolobenzoxazepinone derivatives as non-nucleoside HIV-1 RT inhibitors: further structure-activity relationship studies and identification of more potent broad-spectrum HIV-1 RT inhibitors with antiviral activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 9.70 | 10.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL140665 | — | — | 1 | 10.48 |
| CHEMBL138969 | — | — | 1 | 8.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL140665 | — | EC50 | = | 0.033 | nM | 10.48 |
| CHEMBL138969 | — | EC50 | = | 1.2 | nM | 8.92 |