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Assay Detail

CHEMBL695720

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity for human papillomavirus (HPV6) E1 helicase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism human papillomavirus 11
Confidence 9 — Direct single protein target
Curated By Expert

Target

Replication protein E1 (CHEMBL4953)
Type SINGLE PROTEIN
Organism Human papillomavirus type 11

Publication

Discovery of small-molecule inhibitors of the ATPase activity of human papillomavirus E1 helicase.
Faucher AM, White PW, Brochu C, Grand-Maître C, Rancourt J, Fazal G.
J Med Chem (2004) 47 : 18 -21
PubMed 14695816 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.70 5.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL178590 1 5.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL178590 Ki = 2000.0 nM 5.70