Assay Detail
Functional
CHEMBL695906
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory concentration against human NPC cancer cell line using tetrazolium dye reduction assay (MTT)
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HONE1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Structure-activity and crystallographic analysis of benzophenone derivatives-the potential anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.77 | 8.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL67 | COMBRETASTATIN A4 | -1.0 | 1 | 8.19 |
| CHEMBL9011 | — | — | 1 | 7.45 |
| CHEMBL9309 | — | — | 1 | 7.23 |
| CHEMBL8953 | — | — | 1 | 7.19 |
| CHEMBL276625 | PHENSTATIN | — | 1 | 6.86 |
| CHEMBL8939 | — | — | 1 | 5.29 |
| CHEMBL9241 | — | — | 1 | 5.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL67 | COMBRETASTATIN A4 | IC50 | = | 6.5 | nM | 8.19 |
| CHEMBL9011 | — | IC50 | = | 35.8 | nM | 7.45 |
| CHEMBL9309 | — | IC50 | = | 59.2 | nM | 7.23 |
| CHEMBL8953 | — | IC50 | = | 64.5 | nM | 7.19 |
| CHEMBL276625 | PHENSTATIN | IC50 | = | 138.0 | nM | 6.86 |
| CHEMBL8939 | — | IC50 | = | 5143.4 | nM | 5.29 |
| CHEMBL9241 | — | IC50 | = | 6112.8 | nM | 5.21 |