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Assay Detail

CHEMBL696073

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of herpes simplex virus type 1(HSV-2) in human foreskin fibroblasts cell lines was determined by plaque assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Fibroblast
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

ADMET (CHEMBL612558)
Type ADMET

Publication

Synthesis, antiproliferative, and antiviral activity of certain 4-substituted and 4,5-disubstituted 7-[(1,3-dihydroxy-2-propoxy)methyl]pyrrolo[2,3-d]pyrimidines.
Pudlo JS, Nassiri MR, Kern ER, Wotring LL, Drach JC, Townsend LB.
J Med Chem (1990) 33 : 1984 -1992
PubMed 2163454 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.52 6.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL60469 1 6.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL60469 IC50 = 300.0 nM 6.52