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Assay Detail

CHEMBL696112

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound concentration required to inhibit the viral cell proliferation by 50% against HIV
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human immunodeficiency virus
Confidence 1 — Organism
Curated By Intermediate

Target

Human immunodeficiency virus (CHEMBL613758)
Type ORGANISM
Organism Human immunodeficiency virus

Publication

Synthesis and biological evaluation of a series of 2'-fluorinated-2',3'-dideoxy-2',3'-didehydro-(L)-nucleosides.
Chen SH, Wang Q, Mao J, King I, Dutschman GE, Gullen EA, Cheng YC, Doyle TW.
Bioorg Med Chem Lett (1998) 8 : 1589 -1594
PubMed 9873396 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.44 5.44

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL38887 1 5.44

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL38887 EC50 = 3600.0 nM 5.44