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Assay Detail

CHEMBL696252

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Functional
Inhibition of thrombin induced platelet aggregation was determined in human plasma
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Tissue Plasma
Confidence 1 — Organism
Curated By Intermediate

Target

Homo sapiens (CHEMBL372)
Type ORGANISM
Organism Homo sapiens

Publication

Molecular design and structure--activity relationships leading to the potent, selective, and orally active thrombin active site inhibitor BMS-189664.
Das J, Kimball SD, Hall SE, Han WC, Iwanowicz E, Lin J, Moquin RV, Reid JA, Sack JS, Malley MF, Chang CY, Chong S, Wang-Iverson DB, Roberts DG, Seiler SM, Schumacher WA, Ogletree ML.
Bioorg Med Chem Lett (2002) 12 : 45 -49
PubMed 11738570 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 8.43 8.43

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL356065 1 8.43

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL356065 Kd = 3.715 nM 8.43