Assay Detail
Functional
CHEMBL696411
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested in vitro for its inhibitory activity against U 46619-induced aggregation of human platelet rich plasma (PRP).
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Plasma |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 3. Pyridinylalkyl-substituted 8-[(arylsulfonyl)amino]octanoic acids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.19 | 6.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL138325 | — | — | 1 | 6.55 |
| CHEMBL337331 | — | — | 1 | 6.43 |
| CHEMBL65414 | — | — | 1 | 6.41 |
| CHEMBL136220 | — | — | 1 | 6.22 |
| CHEMBL136845 | — | — | 1 | 5.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL138325 | — | IC50 | = | 280.0 | nM | 6.55 |
| CHEMBL337331 | — | IC50 | = | 370.0 | nM | 6.43 |
| CHEMBL65414 | — | IC50 | = | 390.0 | nM | 6.41 |
| CHEMBL136220 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL136845 | — | IC50 | = | 4600.0 | nM | 5.34 |