Assay Detail
Functional
CHEMBL696433
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Ability to block the eotaxin induced intracellular calcium mobilization in primary human eosinophils was determined
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Discovery of potent and selective phenylalanine derived CCR3 receptor antagonists. Part 2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.15 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL418588 | — | — | 1 | 7.82 |
| CHEMBL33227 | — | — | 1 | 7.42 |
| CHEMBL32493 | — | — | 1 | 6.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL418588 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL33227 | — | IC50 | = | 38.0 | nM | 7.42 |
| CHEMBL32493 | — | IC50 | = | 600.0 | nM | 6.22 |