Assay Detail
Binding
CHEMBL696528
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The binding affinity against IL-1 beta converting enzyme
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Protease inhibitors: current status and future prospects.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.47 | 9.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL115090 | — | — | 1 | 9.43 |
| CHEMBL25943 | — | — | 1 | 8.89 |
| CHEMBL324129 | — | — | 1 | 8.30 |
| CHEMBL114952 | — | — | 1 | 7.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL115090 | — | Ki | = | 0.37 | nM | 9.43 |
| CHEMBL25943 | — | Ki | = | 1.3 | nM | 8.89 |
| CHEMBL324129 | — | Ki | = | 5.0 | nM | 8.30 |
| CHEMBL114952 | — | Ki | = | 54.0 | nM | 7.27 |