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Assay Detail

CHEMBL696529

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
The compound was tested for inhibition of IL-1 beta converting enzyme in whole human blood.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Tissue Blood
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Caspase-1 (CHEMBL4801)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis of a potent, reversible inhibitor of interleukin-1 converting enzyme
Chapman KT
Bioorg Med Chem Lett (1992) 2 : 613 -618
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.12 9.12

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL37630 1 9.12

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL37630 Ki = 0.76 nM 9.12