Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL696769

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In vitro for antiproliferate activity against HaCaT cells
15
Total Activities
15
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HaCaT
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

ADMET (CHEMBL612558)
Type ADMET

Publication

10-omega-phenylalkyl-9(10H)-anthracenones as inhibitors of keratinocyte growth with reduced membrane damaging properties.
Müller K, Breu K.
Bioorg Med Chem Lett (1998) 8 : 3211 -3216
PubMed 9873705 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 15 5.75 6.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL46469 ANTHRALIN 2.0 1 6.16
CHEMBL108976 1 6.05
CHEMBL107703 1 5.96
CHEMBL108767 1 5.75
CHEMBL110990 1 5.52
CHEMBL111358 1 5.42
CHEMBL322702 1 5.39
CHEMBL320940 1 -
CHEMBL108977 1 -
CHEMBL321185 1 -
CHEMBL320780 1 -
CHEMBL109895 1 -
CHEMBL321387 1 -
CHEMBL419569 1 -
CHEMBL109634 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL46469 ANTHRALIN IC50 = 700.0 nM 6.16
CHEMBL108976 IC50 = 900.0 nM 6.05
CHEMBL107703 IC50 = 1100.0 nM 5.96
CHEMBL108767 IC50 = 1800.0 nM 5.75
CHEMBL110990 IC50 = 3000.0 nM 5.52
CHEMBL111358 IC50 = 3800.0 nM 5.42
CHEMBL322702 IC50 = 4100.0 nM 5.39
CHEMBL320940 IC50 > 5000.0 nM -
CHEMBL108977 IC50 < 5000.0 nM -
CHEMBL321185 IC50 > 5000.0 nM -
CHEMBL320780 IC50 > 5000.0 nM -
CHEMBL109895 IC50 > 5000.0 nM -
CHEMBL321387 IC50 < 5000.0 nM -
CHEMBL419569 IC50 < 5000.0 nM -
CHEMBL109634 IC50 > 5000.0 nM -