Assay Detail
Functional
CHEMBL696956
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Compound was evaluated for the antiviral activity against HCMV determined by using Plaque assay
14
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human betaherpesvirus 5 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis, and antiviral activity of certain 2,5,6-trihalo-1-(beta-D-ribofuranosyl)benzimidazoles.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 14 | 5.01 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2093921 | — | — | 1 | 6.16 |
| CHEMBL3143098 | — | — | 1 | 5.82 |
| CHEMBL3143099 | — | — | 1 | 5.70 |
| CHEMBL513232 | — | — | 1 | 5.54 |
| CHEMBL134238 | — | — | 1 | 5.19 |
| CHEMBL182 | GANCICLOVIR | 4.0 | 1 | 5.13 |
| CHEMBL133003 | — | — | 1 | 4.92 |
| CHEMBL605800 | — | — | 1 | 4.52 |
| CHEMBL754 | FOSCARNET SODIUM | 4.0 | 1 | 4.41 |
| CHEMBL603513 | — | — | 1 | 4.40 |
| CHEMBL375530 | DICHLORORIBOBENZIMIDAZOLE | — | 1 | 4.38 |
| CHEMBL71905 | — | — | 1 | 4.00 |
| CHEMBL608318 | — | — | 1 | - |
| CHEMBL608658 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2093921 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL3143098 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL3143099 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL513232 | — | IC50 | = | 2900.0 | nM | 5.54 |
| CHEMBL134238 | — | IC50 | = | 6400.0 | nM | 5.19 |
| CHEMBL182 | GANCICLOVIR | IC50 | = | 7400.0 | nM | 5.13 |
| CHEMBL133003 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL605800 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL754 | FOSCARNET SODIUM | IC50 | = | 39000.0 | nM | 4.41 |
| CHEMBL603513 | — | IC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL375530 | DICHLORORIBOBENZIMIDAZOLE | IC50 | = | 42000.0 | nM | 4.38 |
| CHEMBL71905 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL608318 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL608658 | — | IC50 | > | 100000.0 | nM | - |