Assay Detail
Functional
CHEMBL697019
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested in vitro for its inhibitory activity against U 46619-induced aggregation of washed human platelets.
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 3. Pyridinylalkyl-substituted 8-[(arylsulfonyl)amino]octanoic acids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.99 | 7.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL65414 | — | — | 1 | 7.72 |
| CHEMBL138325 | — | — | 1 | 7.70 |
| CHEMBL136220 | — | — | 1 | 7.57 |
| CHEMBL337331 | — | — | 1 | 6.93 |
| CHEMBL136845 | — | — | 1 | 6.66 |
| CHEMBL136904 | — | — | 1 | 6.52 |
| CHEMBL136905 | — | — | 1 | 5.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL65414 | — | IC50 | = | 19.0 | nM | 7.72 |
| CHEMBL138325 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL136220 | — | IC50 | = | 27.0 | nM | 7.57 |
| CHEMBL337331 | — | IC50 | = | 117.0 | nM | 6.93 |
| CHEMBL136845 | — | IC50 | = | 220.0 | nM | 6.66 |
| CHEMBL136904 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL136905 | — | IC50 | = | 1390.0 | nM | 5.86 |