Assay Detail
Binding
CHEMBL697046
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Kinetic inhibition constant of compound with human Hypoxanthine Phosphoribosyltransferase (HPRT)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Hypoxanthine-guanine phosphoribosyltransferase (CHEMBL2360) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Analysis of 6-(2,2-Dichloroacetamido)chrysene interaction with the hypoxanthine phosphoribosyltransferase from Trypanosoma cruzi.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 4.89 | 5.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL83185 | — | — | 1 | 5.27 |
| CHEMBL87526 | — | — | 1 | 4.96 |
| CHEMBL88057 | — | — | 1 | 4.80 |
| CHEMBL83231 | — | — | 1 | 4.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL83185 | — | Ki | = | 5400.0 | nM | 5.27 |
| CHEMBL87526 | — | Ki | = | 10900.0 | nM | 4.96 |
| CHEMBL88057 | — | Ki | = | 16000.0 | nM | 4.80 |
| CHEMBL83231 | — | Ki | = | 28800.0 | nM | 4.54 |