Assay Detail
Binding
CHEMBL697113
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Binding affinity towards rat histamine H3 receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
The synthesis, and dopamine D2 and serotonin 5-HT3 receptor affinity of 3-aza analogues (pyridyl) of 4-amino-5-chloro-2-methoxybenzamides
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 9.23 | 9.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL301039 | — | — | 1 | 9.50 |
| CHEMBL135410 | — | — | 1 | 9.40 |
| CHEMBL135409 | — | — | 1 | 8.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL301039 | — | Ki | = | 0.3162 | nM | 9.50 |
| CHEMBL135410 | — | Ki | = | 0.3981 | nM | 9.40 |
| CHEMBL135409 | — | Ki | = | 1.585 | nM | 8.80 |