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Assay Detail

CHEMBL697159

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of ADP induced aggregation of human platelets after 15 min of incubation of the drug with PRP prior to the addition of ADP
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Confidence 1 — Organism
Curated By Intermediate

Target

Homo sapiens (CHEMBL372)
Type ORGANISM
Organism Homo sapiens

Publication

Inhibitors of blood platelet cAMP phosphodiesterase. 3. 1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-one derivatives with enhanced aqueous solubility.
Meanwell NA, Dennis RD, Roth HR, Rosenfeld MJ, Smith EC, Wright JJ, Buchanan JO, Brassard CL, Gamberdella M, Gillespie E.
J Med Chem (1992) 35 : 2688 -2696
PubMed 1321911 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.00 7.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL432057 1 7.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL432057 IC50 = 100.0 nM 7.00