Assay Detail
Functional
CHEMBL697178
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive inhibition of the contraction of the human umbilical vein induced by the potent B1 receptor agonist [des-Arg10]-kallidin
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Umbilical vein |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
A rational approach to the design and synthesis of a new bradykinin B(1) receptor antagonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 7.05 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3085458 | — | — | 1 | 8.00 |
| CHEMBL3142392 | — | — | 1 | 6.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3085458 | — | Kd | = | 10.0 | nM | 8.00 |
| CHEMBL3142392 | — | Kd | = | 794.33 | nM | 6.10 |