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Assay Detail

CHEMBL697287

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory concentration gainst Histone deacetylase 1 derived from NIH3T3 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Cell Type NIH3T3
Confidence 9 — Direct single protein target
Curated By Expert

Target

Histone deacetylase 1 (CHEMBL4001)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Antiproliferative and phenotype-transforming antitumor agents derived from cysteine.
Glenn MP, Kahnberg P, Boyle GM, Hansford KA, Hans D, Martyn AC, Parsons PG, Fairlie DP.
J Med Chem (2004) 47 : 2984 -2994
PubMed 15163181 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.00 7.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2000089 TRAPOXIN B 1 7.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2000089 TRAPOXIN B IC50 = 100.0 nM 7.00