Assay Detail

CHEMBL697494

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Inhibitory concentration against partially purified mouse histone deacetylase (HDAC)

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

Histone deacetylase (CHEMBL3832944) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

Histone deacetylase (CHEMBL3832944) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Histone deacetylase

CHEMBL3832944

Anchored from Assay target.

Protein identity Histone deacetylase

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Mus musculus
Confidence	5 — Multiple protein complex / RNA
Curated By	Autocuration

Target

Histone deacetylase (CHEMBL3832944) ↗

Type	PROTEIN FAMILY
Organism	Mus musculus

Publication

Histone deacetylase inhibitors.

Miller TA, Witter DJ, Belvedere S.
J Med Chem (2003) 46 : 5097 -5116
PubMed 14613312 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	8.32	8.84

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL99	TRICHOSTATIN	1.0	1	8.84
CHEMBL314389	OXAMFLATIN	—	1	7.80

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL99	TRICHOSTATIN	IC50	=	1.44	nM	8.84
CHEMBL314389	OXAMFLATIN	IC50	=	15.7	nM	7.80